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The problem is that many drugs create tolerance: an increase in the dose required to produce the same effect, which makes it necessary for the user to increase the dosage or the number of times per day that the drug is taken. As the use of the drug increases, the user may develop a dependence, defined as a need to use a drug or other substance regularly. Dependence can be psychological, in which the drug is desired and has become part of the everyday life of the user, but no serious physical effects result if the drug is not obtained; or physical, in which serious physical and mental effects appear when the drug is withdrawn. Cigarette smokers who try to quit, for example, experience physical withdrawal symptoms, such as becoming tired and irritable, as well as extreme psychological cravings to enjoy a cigarette in particular situations, such as after a meal or when they are with friends. Users may wish to stop using the drug, but when they reduce their dosage they experience withdrawal—negative experiences that accompany reducing or stopping drug use, including physical pain and other symptoms. When the user powerfully craves the drug and is driven to seek it out, over and over again, no matter what the physical, social, financial, and legal cost, we say that he or she has developed an addiction to the drug. For one, even drugs that we do not generally think of as being addictive, such as caffeine, nicotine, and alcohol, can be very difficult to quit using, at least for some people. On the other hand, drugs that are normally associated with addiction, including amphetamines, cocaine, and heroin, do not immediately create addiction in their users. Even for a highly addictive drug like cocaine, only about 15% of users become addicted [1] (Robinson & Berridge, 2003; Wagner & Anthony, 2002). Furthermore, the rate of addiction is lower for those who are taking drugs for medical reasons than for those who are using drugs recreationally. Patients who have become physically dependent on morphine administered during the course of medical treatment for a painful injury or disease are able to be rapidly weaned off [2] the drug afterward, without becoming addicts. Robins, Davis, and Goodwin (1974) found that the majority of soldiers who had become addicted to morphine while overseas were quickly able to stop using after returning home. These drugs are generally illegal and carry with them potential criminal consequences if one is caught and arrested. Snorting ( “sniffing‖) drugs can lead to a loss of the sense of smell, nosebleeds, difficulty in swallowing, hoarseness, and chronic runny nose. Furthermore, the quality and contents of illegal drugs are generally unknown, and the doses can vary substantially from purchase to purchase. Another problem is the unintended consequences of combining drugs, which can produce serious side effects. For instance, ingesting alcohol or benzodiazepines along with the usual dose of heroin is a frequent cause of Attributed to Charles Stangor Saylor.

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Pelvic organs with peritoneum and part of the levator ani muscle have been removed. Anterior portion of thoracic vertebrae removed, dural sheath opened, and spinal cord slightly reflected to the right to display the dorsal and ventral roots. Surface Anatomy of the Lower Limb: Anterior Aspect 477 1 Iliac crest 2 Anterior superior iliac spine 3 Tensor fasciae latae muscle 1 4 Quadriceps femoris muscle 2 5 Iliotibial tract 6 Tendon of biceps femoris muscle 3 7 Patella 8 Patellar ligament 9 Tibia 10 Tendon of tibialis anterior muscle 11 Lateral malleolus 12 Venous network of dorsum of foot 4 13 Iliohypogastric nerve 14 Lateral femoral cutaneous nerve 15 Femoral nerve 16 Common peroneal nerve 5 17 Superficial peroneal nerve 18 Ilio-inguinal nerve 19 Obturator nerve 20 Saphenous nerve 21 Deep peroneal nerve 6 7 8 9 10 11 Cutaneous nerves of the lower limb (anterior aspect). The Inguinal nodes with lymphatic vessels fascia lata and fasciae of the thigh muscles have been removed. The fascia lata has been removed, and the sartorius muscle has been slightly has been removed, and the sartorius muscle has been divided. Sartorius muscle, The sartorius, pectineus, adductor longus, and rectus pectineus muscle, and femoral artery have been cut to femoris muscles have been divided and reflected. The greater part of the femoral artery has been The rectus femoris muscle has been slightly reflected. Sciatic nerve Inferior gluteal artery, vein, and nerve Posterior femoral cutaneous nerve Internal pudendal artery and vein Pudendal nerve C Lesser sciatic foramen Pudendal nerve Internal pudendal artery and vein Red lines 1 Spine-tuber line: the infrapiriform foramen is situated in the middle of this line 2 Spine-trochanter line: the suprapiriform foramen is located in the upper third 3 Tuber-trochanter line: the ischiadic nerve can be found between the middle and posterior third Other structures 4 Posterior superior iliac spine 5 Iliac crest 6 Greater trochanter Gluteal region, right side (postero-lateral aspect). Location of 7 Ischial tuberosity sciatic foramina in relation to the bones (schematic drawing). Notice the position of the foramina above and below the piriformis muscle and the lesser sciatic foramen. Thigh: Posterior Region 485 Gluteal region and posterior region of right thigh (posterior Gluteal region and posterior region of right thigh (posterior aspect). Knee and Popliteal Fossa 487 Right leg, popliteal fossa, middle layer (posterior aspect). Tibial nerve and popliteal vein have been partly removed and a portion of the soleus muscle was cut away to display the anterior tibial artery. Crural Region 491 1 Semimembranosus muscle 2 Semitendinosus muscle 3 Popliteal vein 4 Popliteal artery 5 Tibial nerve 6 Small saphenous vein (cut) 7 Muscular branch of tibial nerve 8 Medial head of gastrocnemius muscle 9 Tendon of plantaris muscle 10 Posterior tibial artery 11 Medial malleolus 12 Biceps femoris muscle 13 Common peroneal nerve 14 Sural arteries 15 Plantaris muscle 16 Lateral head of gastrocnemius muscle 17 Soleus muscle 18 Calcaneal tendon 19 Lateral malleolus 20 Calcaneal tuberosity 21 Sartorius muscle 22 Popliteal artery 23 Tendinous arch of soleus muscle 24 Flexor digitorum longus muscle 25 Flexor retinaculum 26 Peroneal artery 27 Soleus muscle 28 Flexor hallucis longus muscle 29 Anterior tibial artery 30 Muscular branches of tibial nerve 31 Tibialis posterior muscle 32 Communicating branch of peroneal artery 33 Tendon of tibialis anterior muscle 34 Tibia 35 Tendon of extensor hallucis longus muscle 36 Tendons of extensor digitorum longus muscle 37 Anterior tibialis artery 38 Fibula 39 Tendons of peroneus longus and brevis muscles Right leg, posterior crural region, deepest layer (posterior Cross section of the leg, superior to the malleoli aspect).

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10 of 10 - Review by K. Kelvin
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Total customer reviews: 95