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Other prosopagnosic subjects can perceive these different stages occur in separate anatomic structures, facial structure accurately but on tests of facial imagery can- some neuroanatomic models suggest that this may be the not recall the faces of familiar people, indicating an “associa- case. However, this is a relative rather the encoding of the structural information about the face. However, these should be supplemented by objec- Diagnosis Tests of face familiarity tive tests for diagnosis. The hallmark of prosopagnosia is the reduced ability of sub- jects to realize that they have seen a face before: hence, key Exclusionary tests diagnostic tests probe the sense of familiarity for previously Establishing impaired face recognition is not suffcient for the seen faces. One must also show that this is less sensitive because their stimuli could allow subjects to not due to more general problems with vision and memory. For this reason, challenging tests degree of short-term familiarity with the faces seen during of object recognition that include measures of reaction time and premorbid expertise44 are useful (see “Objects” section). Tests of familiarity for famous faces are also used, but such tests depend on the person having seen those celebri- Finally, face identity recognition defcits can occur in ties before, and are therefore affected by age, education, and the context of other disorders, and the diagnostic process cultural background. In prosopagnosic subjects, this can be should consider whether any of these are present. In children, this includes conditions such as autism45–48 and Turner’s compounded by the fact that these subjects may lose interest syndrome, 49 while in adults impaired face recognition has in flms and television because they cannot keep track of the been reported in schizophrenia, 50, 51 Alzheimer’s disease, 52–54 characters, thus limiting their exposure to newer celebrities. The diagnosis of Tests of face perception prosopagnosia should be reserved for cases in which poor Tests of face perception – that is, the ability to perceive dif- face recognition cannot be explained by one of these other ferences between faces – do not establish the diagnosis of conditions. What they can do is demonstrate if prosop- and developmental prosopagnosia are outlined in Table 1. Defcits in face perception have been measured by the Cambridge Face specifcity Face Perception Test39 and the Glasgow Face Matching Test, 40 Are prosopagnosic subjects impaired in the recognition of which involve sorting or matching faces by their identity faces only? There is a 15-item self-report questionnaire13 theories have proposed that words and faces, two visual that contains questions on face recognition, attractiveness classes for which literate humans have great expertise, judgments, and expression recognition, and a more recent share and compete for resources, leading to predictions that 20-item questionnaire for face identity (Prosopagnosia Index, prosopagnosic subjects may have subtle defcits in word Eye and Brain 2016:8 submit your manuscript| www. However, individual data were analyzed before extrastriate cortex: whether the processing of faces and controlling for expertise, making it diffcult to know whether objects diverges later is the question. Neuroimaging studies expertise-adjusted car recognition was intact in each subject. Although face dissociation between face and object processing: stimulation processing is more active in the right hemisphere and word of face areas interrupts face processing more than object pro- processing on the left, both show bilateral networks that over- cessing and stimulation of object areas results in the reverse.

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